Neuroscience Education Institute in Carlsbad, CA, USA.
CNS Spectr. 2009 Nov;14(11 Suppl 10):3-6; quiz 7-8. doi: 10.1017/s1092852900003837.
Individuals with major depressive disorder (MDD) have high rates of disability, morbidity, and mortality, and are responsible for as many as one-fourth of all healthcare visits. Within primary care settings, 5% to 10% of adults have MDD, but only one-third of those are diagnosed. Thus, despite the devastating decrease in the quality-of-life and productivity of patients, depression is often under-diagnosed and therefore inadequately treated. Most patients with depression who are adherent with their treatment plan still experience residual symptoms, and require lon-term treatment. Adequately managing residual symptoms will hopefully lead to increased remission in these patients. This supplement focuses on the different types of residual symptoms that patients experience and suggests various treatment options.
患有重度抑郁症（MDD）的个体残疾率、发病率和死亡率较高，占所有医疗就诊的比例高达四分之一。在初级保健环境中，5%至 10%的成年人患有 MDD，但只有三分之一的人被诊断出来。因此，尽管患者的生活质量和生产力严重下降，但抑郁症常常被漏诊，因此治疗不足。大多数坚持治疗计划的抑郁症患者仍会出现残留症状，需要长期治疗。妥善管理残留症状有望增加这些患者的缓解率。本增刊重点介绍了患者所经历的不同类型的残留症状，并提出了各种治疗选择。
