Ondokuz Mayis University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Turkey.
Med Oral Patol Oral Cir Bucal. 2010 Jul 1;15(4):e649-52.
Masseter muscle hypertrophy is a rare condition of unknown cause which is important in the differential diagnosis of head and neck masses, located in the cheek. Several treatment options reported for masseter hypertrophy, which range from simple pharmacotherapy to more invasive surgical reduction. Botulinum toxin type A is a powerful neurotoxin which is produced by the anaerobic organism Clostridium botulinum and when injected into a muscle causes interference with the neurotransmitter mechanism producing selective paralysis and subsequent atrophy of the muscle. Injection of botulinum toxin type A into the masseter muscle is generally considered a less invasive modality and has been advocated for cosmetic sculpting of the lower face. Botulinum toxin type A injection is considered to be a beneficial treatment modality in masseter muscle hypertrophy patients. The aim of this article is to report two cases of masseteric muscle hypertrophy which were treated with botulinum toxin type A injection. Marked changes in facial feature were achieved 3 months after the procedure.
咬肌肥大是一种病因不明的罕见病症，在鉴别位于面颊部的头颈部肿块时非常重要。目前已经报道了多种针对咬肌肥大的治疗方法，包括从简单的药物治疗到更具侵入性的手术切除。A型肉毒毒素是一种由厌氧微生物肉毒梭菌产生的强力神经毒素，当注入肌肉时，它会干扰神经递质机制，导致肌肉选择性瘫痪和随后的萎缩。将肉毒毒素 A 注射到咬肌中通常被认为是一种侵入性较小的方法，并已被提倡用于对面下部进行美容塑形。肉毒毒素 A 注射被认为是治疗咬肌肥大患者的一种有益治疗方法。本文旨在报告两例接受肉毒毒素 A 注射治疗的咬肌肥大病例。治疗 3 个月后，面部特征有明显改变。
