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[A型肉毒杆菌毒素治疗影响美观的咬肌肥大]

[Botulinum toxin type A treatment of cosmetically disturbing masseteric hypertrophy].

作者信息

Rijsdijk B A, van ES R J, Zonneveld F W, Steenks M H, Koole R

机构信息

Academisch Ziekenhuis, Utrecht.

出版信息

Ned Tijdschr Geneeskd. 1998 Mar 7;142(10):529-32.

PMID:9623101
Abstract

Two patients, a woman aged 21 and a man aged 29, with asymmetrical swellings of both mandibular angles and a painful, heavy sensation in the masticatory muscles (and in the woman also round the maxillary joint), were diagnosed as having hypertrophy of the masseter muscles. Both had the habit of jaw clenching and tooth grinding. Treatment consisted not of the traditional surgical debulking which also allows correction of overdeveloped osseous mandibular angles, but of injections with botulinum toxin type A. Injection of 40-60 IU (product: Botox) per muscle was followed by some atrophy; cosmetically satisfactory results were achieved after repetition of the treatment a few months later. Reduction of muscle volume was confirmed by a quantitative volumetric assessment of MRI scans. In the female patient, the pain also abated.

摘要

两名患者,一名21岁女性和一名29岁男性,双侧下颌角不对称肿胀,咀嚼肌有疼痛、沉重感(女性患者上颌关节周围也有此症状),被诊断为咬肌肥大。两人都有紧咬牙关和磨牙的习惯。治疗方法并非传统的手术减容(手术还可矫正过度发育的下颌角骨质),而是注射A型肉毒杆菌毒素。每块肌肉注射40 - 60国际单位(产品:保妥适)后出现了一些萎缩;几个月后重复治疗取得了令人满意的美容效果。通过MRI扫描的定量容积评估证实了肌肉体积的减小。在女性患者中,疼痛也减轻了。

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