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检测慢性难治性牙周炎患者龈下生物膜中的粪肠球菌。

Detection of enterococcus faecalis in subgingival biofilm of patients with chronic refractory periodontitis.

机构信息

Department of Community Dentistry, Tabriz Dental Faculty, Iran.

出版信息

Med Oral Patol Oral Cir Bucal. 2010 Jul 1;15(4):e667-70. doi: 10.4317/medoral.15.e667.

Abstract

OBJECTIVES

Refractory periodontitis is the occurrence of additional clinical attachment loss after repeated attempts to control the infection with conventional periodontal therapy. Some microorganisms seem to be involved in the pathogenesis of chronic refractory periodontitis. The prevalence of Enterococcus faecalis in the oral cavity seems to be higher in individuals with periodontitis. Therefore, the present study investigated the presence of E. faecalis in subgingival biofilm of patients with chronic refractory periodontal disease.

STUDY DESIGN

Periodontal treatment was instituted for 100 patients suffering from chronic periodontitis. Then samples were obtained from 27 successfully treated and 27 chronic refractory periodontitis subjects and then cultured. Statistical evaluation was performed for descriptive purposes.

RESULTS

27% of the patients had chronic refractory periodontitis. The difference in the presence of E. faecalis in the pockets between the successfully treated (11.1%) and chronic refractory (51.8%) groups by culture methods was statistically significant (p<0.05).

CONCLUSION

Data showed that E. faecalis is probably involved in the pathogenesis of refractory periodontitis. Accurate knowledge about the pathogen and its role in the pathogenesis of refractory infections helps develop effective treating strategies.

摘要

目的

难治性牙周炎是指在常规牙周治疗反复尝试控制感染后仍出现额外的临床附着丧失。一些微生物似乎参与了慢性难治性牙周炎的发病机制。口腔中粪肠球菌的患病率似乎在牙周炎患者中更高。因此,本研究调查了慢性难治性牙周病患者龈下生物膜中是否存在粪肠球菌。

研究设计

对 100 名患有慢性牙周炎的患者进行牙周治疗。然后从 27 名成功治疗的和 27 名慢性难治性牙周炎患者中获取样本并进行培养。为了描述性目的进行了统计评估。

结果

27%的患者患有慢性难治性牙周炎。通过培养方法,成功治疗组(11.1%)和慢性难治性组(51.8%)的袋内粪肠球菌检出率差异有统计学意义(p<0.05)。

结论

数据表明,粪肠球菌可能参与了难治性牙周炎的发病机制。准确了解病原体及其在难治性感染发病机制中的作用有助于制定有效的治疗策略。

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