Jian Zhongping, Yu Lingfeng, Rao Bin, Tromberg Bruce J, Chen Zhongping
Beckman Laser Institute, University of California, Irvine, California 92612, USA.
Opt Express. 2010 Jan 18;18(2):1024-32. doi: 10.1364/OE.18.001024.
Optical coherence tomography is an emerging non-invasive technology that provides high resolution, cross-sectional tomographic images of internal structures of specimens. OCT images, however, are usually degraded by significant speckle noise. Here we introduce to our knowledge the first 3D approach to attenuating speckle noise in OCT images. Unlike 2D approaches which only consider information in individual images, 3D processing, by analyzing all images in a volume simultaneously, has the advantage of also taking the information between images into account. This, coupled with the curvelet transform's nearly optimal sparse representation of curved edges that are common in OCT images, provides a simple yet powerful platform for speckle attenuation. We show the approach suppresses a significant amount of speckle noise, while in the mean time preserves and thus reveals many subtle features that could get attenuated in other approaches.
光学相干断层扫描是一种新兴的非侵入性技术，可提供标本内部结构的高分辨率横截面断层图像。然而，OCT图像通常会因显著的散斑噪声而退化。在此，据我们所知，我们首次引入了一种用于衰减OCT图像中散斑噪声的三维方法。与仅考虑单个图像中信息的二维方法不同，三维处理通过同时分析一个体积中的所有图像，还具有将图像之间的信息考虑在内的优势。这与曲波变换对OCT图像中常见的弯曲边缘几乎最优的稀疏表示相结合，为散斑衰减提供了一个简单而强大的平台。我们表明，该方法抑制了大量的散斑噪声，同时保留并因此揭示了许多在其他方法中可能会被衰减的细微特征。
