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IEEE Trans Neural Netw. 1999;10(3):499-507. doi: 10.1109/72.761707.
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Translational principles of deep brain stimulation.脑深部电刺激的转化原理
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7
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Neuronal oscillators in aplysia californica that demonstrate weak coupling in vitro.加州海兔中表现出体外弱耦合的神经元振荡器。
Phys Rev Lett. 2005 Sep 23;95(13):138103. doi: 10.1103/PhysRevLett.95.138103.

一种用于设计复杂节律系统集体行为的框架。

A Framework for Engineering the Collective Behavior of Complex Rhythmic Systems.

作者信息

Rusin Craig G, Kiss István Z, Kori Hiroshi, Hudson John L

机构信息

Department of Chemical Engineering, University of Virginia, Charlottesville, VA 22904, USA.

出版信息

Ind Eng Chem Res. 2009 Mar 16;48(21):9416. doi: 10.1021/ie801807.

DOI:10.1021/ie801807
PMID:20174453
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2822350/
Abstract

We have developed an engineering framework which utilizes experiment-based phase models to tune complex dynamic structures to desired states; weak, non-destructive signals are employed to alter interactions among nonlinear rhythmic elements. In this manuscript we present an integrated overview and discussion of our recent studies in this area. Experiments on electrochemical reactions were conducted using multi-electrode arrays to demonstrate the use of mild model-engineered feedback to achieve a desirable system response. Application is made to the tuning of phase difference between two oscillators, generation of sequentially-visited dynamic cluster patterns, engineering dynamically differentiated cluster states, and to the design of a nonlinear anti-pacemaker for the destruction of synchronization of a population of interacting oscillators.

摘要

我们已经开发了一个工程框架,该框架利用基于实验的相位模型将复杂的动态结构调整到期望状态;采用微弱、非破坏性信号来改变非线性节律元素之间的相互作用。在本手稿中,我们对该领域的近期研究进行了综合概述和讨论。使用多电极阵列进行了电化学反应实验,以证明使用温和的模型工程反馈来实现理想的系统响应。该方法应用于两个振荡器之间相位差的调整、顺序访问动态簇模式的生成、动态区分簇状态的工程设计,以及用于破坏相互作用振荡器群体同步的非线性反起搏器的设计。