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本文引用的文献

1
Guideline for the management of nonmuscle invasive bladder cancer (stages Ta, T1, and Tis): 2007 update.非肌层浸润性膀胱癌（Ta、T1和Tis期）管理指南：2007年更新版
J Urol. 2007 Dec;178(6):2314-30. doi: 10.1016/j.juro.2007.09.003.
2
Risk of post-operative intravesical mitomycin C instillation following transurethral bladder tumor resection.经尿道膀胱肿瘤切除术后膀胱内灌注丝裂霉素C的风险
Can J Urol. 2006 Dec;13(6):3317-20.
3
Bladder perforation: a potential risk of early endovesical chemotherapy with mitomycin C.膀胱穿孔：丝裂霉素C早期膀胱内化疗的潜在风险。
Urol Int. 2005;75(4):373-5. doi: 10.1159/000089179.
4
Unusual complication after immediate postoperative intravesical mitomycin C instillation.
Eur Urol. 2003 Jun;43(6):711-2. doi: 10.1016/s0302-2838(03)00151-9.
5
Perioperative single dose instillation of epirubicin or interferon-alpha after transurethral resection for the prophylaxis of primary superficial bladder cancer recurrence: a prospective randomized multicenter study--FinnBladder III long-term results.经尿道切除术后围手术期单次剂量灌注表柔比星或α干扰素预防原发性浅表性膀胱癌复发：一项前瞻性随机多中心研究——芬兰膀胱研究III长期结果
J Urol. 2002 Sep;168(3):981-5. doi: 10.1016/S0022-5347(05)64556-9.
6
Perivesical inflammation after early mitomycin C instillation.早期丝裂霉素C灌注后膀胱周围炎症。
BJU Int. 2000 Mar;85(4):556-7. doi: 10.1046/j.1464-410x.2000.00539.x.
7
Perivesical fat necrosis after adjuvant intravesical chemotherapy.辅助性膀胱内化疗后膀胱周围脂肪坏死
BJU Int. 1999 Mar;83(4):420-3. doi: 10.1046/j.1464-410x.1999.00951.x.
8
Effectiveness of a single immediate mitomycin C instillation in patients with low risk superficial bladder cancer: short and long-term followup.单次即刻膀胱灌注丝裂霉素C治疗低危浅表性膀胱癌患者的疗效：短期和长期随访
J Urol. 1999 Apr;161(4):1120-3.
9
A prospective European Organization for Research and Treatment of Cancer Genitourinary Group randomized trial comparing transurethral resection followed by a single intravesical instillation of epirubicin or water in single stage Ta, T1 papillary carcinoma of the bladder.一项欧洲癌症研究与治疗组织泌尿生殖系统肿瘤组的前瞻性随机试验，比较经尿道切除术联合单次膀胱内灌注表柔比星或水用于单发Ta、T1期膀胱乳头状癌的单阶段治疗。
J Urol. 1993 Apr;149(4):749-52. doi: 10.1016/s0022-5347(17)36198-0.
10
Intravesical adjuvant chemotherapy for superficial transitional cell bladder carcinoma: results of 2 European Organization for Research and Treatment of Cancer randomized trials with mitomycin C and doxorubicin comparing early versus delayed instillations and short-term versus long-term treatment. European Organization for Research and Treatment of Cancer Genitourinary Group.
J Urol. 1995 Mar;153(3 Pt 2):934-41.

术后即刻膀胱内灌注丝裂霉素C后发生膀胱穿孔。

Bladder perforation after immediate postoperative intravesical instillation of mitomycin C.

作者信息

Lim Darwin, Izawa Jonathan I, Middlebrook Paul, Chin Joseph L

机构信息

Departments of Surgery & Oncology, Divisions of Urology & Surgical Oncology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON;

出版信息

Can Urol Assoc J. 2010 Feb;4(1):E1-3. doi: 10.5489/cuaj.781.

DOI:10.5489/cuaj.781
PMID:20174483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2825029/
Abstract

Intravesical chemotherapy after transurethral resection of a bladder tumour (TURBT) has been observed to significantly decrease recurrence rates compared to TURBT alone. Though immediate postoperative intravesical treatment with chemotherapeutic agents after transurethral resection for superficial bladder carcinoma is generally considered a safe and effective adjunctive therapy in decreasing recurrence rates, its instillation is not always completely innocuous. Lately, a more serious complication of bladder perforation associated with immediate instillation of intravesical mitomycin C (MMC) after TURBT was reported. We report our own experience of a male patient with bladder perforation after an early instillation of a single dose of MMC. In this case, systemic toxicity occurred which required intensive care after surgical repair.

摘要

经尿道膀胱肿瘤电切术（TURBT）后膀胱内化疗与单纯TURBT相比，已观察到可显著降低复发率。虽然经尿道浅表性膀胱癌电切术后立即膀胱内使用化疗药物治疗通常被认为是降低复发率的一种安全有效的辅助治疗方法，但其灌注并非总是完全无害。最近，有报道称TURBT后立即灌注膀胱内丝裂霉素C（MMC）会出现更严重的膀胱穿孔并发症。我们报告了1例男性患者在早期单次灌注MMC后发生膀胱穿孔的自身经验。在该病例中，出现了全身毒性反应，手术修复后需要重症监护。