Katkoori Devendar, Cohen Brian L, Soloway Mark S, Manoharan Murugesan
Senior research associate, Department of Urology;
Can Urol Assoc J. 2010 Feb;4(1):E4-6. doi: 10.5489/cuaj.782.
Small cell carcinoma (SCC) of the urinary bladder is a rare disease accounting for 0.5% to 0.7% of all primary bladder cancers. Transplant recipients are a special subset of patients with increased risk for various urologic malignancies, including transitional cell carcinoma of the bladder. However, to the best of our knowledge, a SCC of the urinary bladder has not been reported in transplant recipients. We report what we believe are the first 2 reported cases of transplant recipients with SCC of the bladder. Small cell carcinoma was diagnosed 5 years after transplantation in both patients and they died due to metastatic SCC. Our report emphasizes the highly aggressive nature of SCC and also the rapid progression seen in transplant recipients.
膀胱小细胞癌（SCC）是一种罕见疾病，占所有原发性膀胱癌的0.5%至0.7%。移植受者是患各种泌尿系统恶性肿瘤风险增加的特殊患者群体，包括膀胱移行细胞癌。然而，据我们所知，尚未有移植受者发生膀胱SCC的报道。我们报告了我们认为是首例的2例移植受者发生膀胱SCC的病例。两名患者均在移植后5年被诊断为小细胞癌，且均因转移性SCC死亡。我们的报告强调了SCC的高度侵袭性以及在移植受者中所见的快速进展。
