Ramirez I
Monell Chemical Senses Center, Philadelphia, PA 19104-3308.
Physiol Behav. 1991 Jan;49(1):89-92. doi: 10.1016/0031-9384(91)90236-h.
The development of susceptibility to dietary hyperphagia was examined in two strains of rats. Juvenile Lewis and CD rats fed a wet diet initially eat less energy than do rats fed the same diet in dry form. As the rats approach adulthood, rats fed the wet diet consume more energy than rats fed the dry diet. Lewis rats began displaying hyperphagia at an earlier age than did CD rats. However, Lewis rats, unlike CD rats, fed dry diet during the juvenile stage and subsequently switched to wet diets, displayed only transient hyperphagia. Variability between animals within a group was substantially smaller in Lewis than in CD rats, indicating that genetic factors may be responsible for the differences between the two strains. Thus, susceptibility to dietary hyperphagia is influenced by interactions between strain of rat, age of testing, and type of diet fed in the juvenile stage.
在两种品系的大鼠中研究了饮食性多食易感性的发展情况。幼年的刘易斯大鼠和CD大鼠最初喂食湿性饲料时摄入的能量比喂食相同干性饲料的大鼠少。随着大鼠接近成年期，喂食湿性饲料的大鼠比喂食干性饲料的大鼠消耗更多能量。刘易斯大鼠比CD大鼠在更早的年龄开始表现出多食。然而，与CD大鼠不同的是，刘易斯大鼠在幼年阶段喂食干性饲料，随后换成湿性饲料，仅表现出短暂的多食。刘易斯大鼠组内动物之间的变异性比CD大鼠组内的变异性小得多，这表明遗传因素可能是这两个品系之间差异的原因。因此，饮食性多食的易感性受大鼠品系、测试年龄和幼年阶段所喂食的饲料类型之间相互作用的影响。
