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从基因组数据库中挖掘新型生物脱硫微生物。

Mining of genomic databases to identify novel biodesulfurizing microorganisms.

机构信息

Center for Energy Studies, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.

出版信息

J Ind Microbiol Biotechnol. 2010 Apr;37(4):425-9. doi: 10.1007/s10295-010-0697-6. Epub 2010 Feb 20.

Abstract

The commercialization of the biocatalytic desulfurization process does not seem to be realistic in the near future because of the low desulfurization rate of the known microorganisms. Hence, the future development will depend on either genetically modifying the currently available bacteria or identifying novel biodesulfurizers. In this study an in silico method to identify new biodesulfurizing microorganisms was adopted. By screening the available genomic databases, 13 novel desulfurizing microorganisms belonging to 12 genera were identified. Several of these could be of immense utility as they have both environment pollutant and industrial waste degrading capability.

摘要

由于已知微生物的脱硫率较低,生物催化脱硫工艺在近期内似乎不太可能实现商业化。因此,未来的发展将取决于对现有细菌进行基因改造或鉴定新的生物脱硫剂。在这项研究中,采用了一种计算机模拟方法来鉴定新的生物脱硫微生物。通过筛选现有的基因组数据库,鉴定出了 13 种属于 12 个属的新型脱硫微生物。其中有几种可能具有巨大的用途,因为它们既具有环境污染物降解能力,又具有工业废物降解能力。

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