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韧带样瘤:“良性”肿瘤,而非良性疾病。

The desmoid tumor: "benign" neoplasm, not a benign disease.

作者信息

Méndez-Fernández M A, Gard D A

机构信息

Division of Plastic Surgery, Methodist Hospital, Houston, Texas.

出版信息

Plast Reconstr Surg. 1991 May;87(5):956-60. doi: 10.1097/00006534-199105000-00025.

DOI:10.1097/00006534-199105000-00025
PMID:2017508
Abstract

The desmoid tumor is a rare neoplasm which, because of its histopathologic appearance, has been traditionally considered to be benign. Despite its benign microscopic features, it has an aggressive local behavior and, if not excised adequately, has a tendency to recur locally and invade neighboring structures with significant potential for morbidity, deformity, or even death. Two cases of recurrent extraabdominal desmoid tumors are presented not only because they are highly representative of this disease, but also because they emphasize the need for aggressive surgical treatment. Also, they are unusual and challenging cases from a reconstructive standpoint. Based on this experience and on the most recent literature, we believe that this tumor, regardless of its microscopic features, should be addressed and treated as a malignancy.

摘要

硬纤维瘤是一种罕见的肿瘤,由于其组织病理学表现,传统上被认为是良性的。尽管其具有良性的微观特征,但它具有侵袭性的局部行为,如果切除不充分,有局部复发并侵犯邻近结构的倾向,具有导致严重并发症、畸形甚至死亡的重大风险。本文报告两例复发性腹外硬纤维瘤,不仅因为它们是这种疾病的高度典型病例,还因为它们强调了积极手术治疗的必要性。此外,从重建的角度来看,它们是不寻常且具有挑战性的病例。基于这一经验和最新文献,我们认为这种肿瘤,无论其微观特征如何,都应作为恶性肿瘤来处理和治疗。

相似文献

1
The desmoid tumor: "benign" neoplasm, not a benign disease.韧带样瘤:“良性”肿瘤,而非良性疾病。
Plast Reconstr Surg. 1991 May;87(5):956-60. doi: 10.1097/00006534-199105000-00025.
2
Giant recurrent desmoid tumor: a case report.巨大复发性硬纤维瘤:一例报告
Am Surg. 1977 Sep;43(9):613-6.
3
Thirty years of experience with desmoid tumors at Charity Hospital.
Am Surg. 1987 Jun;53(6):318-9.
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Juvenile aponeurotic fibroma: a case report.青少年腱膜纤维瘤:一例报告
J Hand Surg Am. 1977 Jul;2(4):258-60. doi: 10.1016/s0363-5023(77)80120-2.
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The desmoid tumor. Not a benign disease.硬纤维瘤。并非良性疾病。
Arch Surg. 1989 Feb;124(2):191-6. doi: 10.1001/archsurg.1989.01410020061010.
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Desmoid tumors of the chest wall. A locally recurrent problem.胸壁硬纤维瘤。一个局部复发问题。
J Thorac Cardiovasc Surg. 1992 Oct;104(4):900-3.
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Desmoid-type fibromatosis-associated Gardner fibromas: prevalence and impact on local recurrence.Desmoid 型纤维瘤病相关 Gardner 纤维瘤:患病率及对局部复发的影响。
Cancer Lett. 2014 Oct 28;353(2):176-81. doi: 10.1016/j.canlet.2014.07.020. Epub 2014 Jul 23.
8
[Abdominal desmoid tumor].[腹壁硬纤维瘤]
Minerva Chir. 1993 Feb;48(3-4):163-6.
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[Diagnosis and therapy of aggressive fibromatosis (extra-abdominal desmoid) in the head and neck area].
Laryngorhinootologie. 1991 Jul;70(7):367-74. doi: 10.1055/s-2007-998055.
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[Desmoid tumors].[硬纤维瘤]
Harefuah. 1992 Jul;123(1-2):20-2, 71.

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Desmoid tumor following abdominally-based free flap breast reconstruction.腹部游离皮瓣乳房重建术后的硬纤维瘤
Gland Surg. 2017 Feb;6(1):89-92. doi: 10.21037/gs.2016.06.01.
2
Desmoid tumours: our experience of six cases and review of literature.硬纤维瘤:我们的6例经验及文献综述
J Clin Diagn Res. 2014 Oct;8(10):NE01-4. doi: 10.7860/JCDR/2014/9610.5032. Epub 2014 Oct 20.
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The analysis of treatment of aggressive fibromatosis using oral methotrexate chemotherapy.口服甲氨蝶呤化疗治疗侵袭性纤维瘤病的分析
Clin Orthop Surg. 2014 Dec;6(4):439-42. doi: 10.4055/cios.2014.6.4.439. Epub 2014 Nov 10.
4
An unusual case of chest wall desmoid tumor.一例罕见的胸壁硬纤维瘤病例。
Indian J Surg. 2010 Jul;72(Suppl 1):336-8. doi: 10.1007/s12262-010-0090-8. Epub 2010 Oct 20.
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Desmoid tumors of the chest wall: surgical challenges and possible risk factors.胸壁硬纤维瘤:手术挑战与潜在风险因素
Clinics (Sao Paulo). 2011;66(4):705-8. doi: 10.1590/s1807-59322011000400028.
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[Desmoid tumors of the chest wall: report of 12 cases].[胸壁硬纤维瘤:12例报告]
Pan Afr Med J. 2009 Nov 10;3:13.
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Huge intrathoracic desmoid tumor.巨大的胸腔内硬纤维瘤。
Ann Thorac Med. 2009 Jul;4(3):146-8. doi: 10.4103/1817-1737.53350.
8
[Extra-abdominal desmoid tumors. Case report and literature review].[腹外硬纤维瘤。病例报告及文献综述]
HNO. 2005 Jul;53(7):639-44. doi: 10.1007/s00106-004-1134-9.
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Congenital desmoid tumor of the scalp: a histologically benign lesion with aggressive clinical behavior.头皮先天性硬纤维瘤:一种组织学上为良性但临床行为具有侵袭性的病变。
Childs Nerv Syst. 1996 Jul;12(7):409-12. doi: 10.1007/BF00395097.