The Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway.
Acta Neurol Scand. 2010 Dec;122(6):418-24. doi: 10.1111/j.1600-0404.2010.01332.x.
We investigated caregiver distress associated with neuropsychiatric problems in patients with newly diagnosed Parkinson's disease (PD).
Persons who were next of kins of 198 patients and 168 healthy individuals completed the Neuropsychiatric Inventory Caregiver Distress Scale.
Even at the time of diagnosis PD has a considerable impact on the next of kins' experience of distress. Nearly 50% reported distress, significantly more than in the control group, and more than one-quarter reported moderate severe distress. Except the more rarely reported neuropsychiatric symptoms, apathy was the symptom that most frequently caused caregiver distress in PD patient's next of kin (94.5%), followed by depression (88.2%), anxiety (86.2%) and irritability (83.3%).
The study underlines the importance of focusing on neuropsychiatric aspects in patients and associated caregiver distress even in early PD management.
我们研究了伴有新发帕金森病（PD）患者神经精神问题的照料者的痛苦。
198 名患者及其 168 名健康对照者的直系亲属完成了神经精神疾病问卷照料者痛苦量表。
甚至在诊断时 PD 就对直系亲属的痛苦体验产生相当大的影响。近 50%的人报告有痛苦，显著多于对照组，且超过四分之一的人报告有中度至重度痛苦。除了较少报告的神经精神症状外，淡漠是 PD 患者的直系亲属最常引起照料者痛苦的症状（94.5%），其次是抑郁（88.2%）、焦虑（86.2%）和易激惹（83.3%）。
本研究强调了即使在早期 PD 管理中，也应关注患者的神经精神方面及其相关照料者痛苦。
Zotero 插件