缺血性中风的遗传学。
The genetics of ischaemic stroke.
机构信息
Laboratory of Neurogenetics, NIA/NIH, Bethesda, MD, USA.
出版信息
J Intern Med. 2010 Feb;267(2):139-55. doi: 10.1111/j.1365-2796.2009.02202.x.
Abstract
In this review, we discuss the genetic factors in both the aetiology and treatment of ischaemic stroke. We discuss candidate gene association studies, family linkage studies and the more recent whole genome association studies and whole genome expression studies. We also briefly discuss genetic testing for stroke risk and genetic analysis of treatment complications.
摘要
在这篇综述中，我们讨论了缺血性中风的病因和治疗中的遗传因素。我们讨论了候选基因关联研究、家族连锁研究以及最近的全基因组关联研究和全基因组表达研究。我们还简要讨论了中风风险的基因检测和治疗并发症的基因分析。
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本文引用的文献
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Genomewide association studies of stroke.中风的全基因组关联研究。
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Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion.WNK1基因的多态性与血压变化及尿钾排泄有关。
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