Department of Neonatology and Pediatric Intensive Care, Vest Children's Hospital, University of Witten-Herdecke, Datteln, Germany.
J Pediatr. 2010 Mar;156(3):490-1. doi: 10.1016/j.jpeds.2009.10.033.
Caffeine improves the rate of survival without neurodevelopmental disability in preterm infants. The mechanisms underlying neuroprotection are incompletely understood. In 51 preterm infants studied by amplitude-integrated electroencephalography from 2 hours before to 2 hours after intravenous caffeine administration, we found that caffeine increases amplitudes and periods of continuity.
咖啡因可提高早产儿的存活率而不伴有神经发育障碍。其神经保护机制尚未完全阐明。通过对 51 例早产儿进行静脉注射咖啡因前 2 小时至后 2 小时的振幅整合脑电图研究,我们发现咖啡因可增加振幅和连续性周期。