Computational Biomedicine Laboratory, Department of Computer Science, University of Houston, TX 77204, USA.
IEEE Trans Biomed Eng. 2010 Aug;57(8):1886-96. doi: 10.1109/TBME.2010.2043254. Epub 2010 Feb 18.
In this paper, we present a physics-based deformable model framework for morphological and motion analysis of the left anterior descending (LAD) coronary artery. The proposed model is designed to capture the complex motion that the LAD undergoes during the cardiac cycle. The key idea is to define a local coordinate system for the heart and to parameterize both the shape and motion of the LAD in a single framework. The shape of the LAD is modeled as a parametric generalized cylinder, and the motion during the heart cycle is modeled as a composite of three components, which are as follows: 1) longitudinal deformation, 2) radial displacement, and 3) angular displacement over the cardiac cycle. The proposed framework for the LAD shape-motion estimation is generic, since it does not assume any particular tubular shape. Results obtained for four human subjects using electron beam computed tomography data are in agreement with LAD shape-motion deformations reported in the literature.
在本文中，我们提出了一种基于物理的可变形模型框架，用于左前降支（LAD）冠状动脉的形态和运动分析。所提出的模型旨在捕获 LAD 在心动周期中经历的复杂运动。其关键思想是为心脏定义一个局部坐标系，并在单个框架中对 LAD 的形状和运动进行参数化。LAD 的形状被建模为参数化的广义圆柱，而在心动周期期间的运动被建模为三个分量的组合，分别为：1）纵向变形，2）径向位移，以及 3）在心动周期期间的角度位移。所提出的 LAD 形状-运动估计框架是通用的，因为它不假设任何特定的管状形状。使用电子束计算机断层扫描数据对四个人体对象进行的结果与文献中报告的 LAD 形状-运动变形一致。
