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一种用于使用各种平滑滤波器研究PET重建中肿瘤信号和噪声的体模:实验及与模拟强度扩散的比较

A phantom for investigation of tumour signal and noise in PET reconstruction with various smoothing filters: experiments and comparisons with simulated intensity diffusion.

作者信息

Skretting A, Glomset O, Bogsrud T V

机构信息

The Interventional Centre, Oslo University Hospital, Oslo.

出版信息

Radiat Prot Dosimetry. 2010 Apr-May;139(1-3):191-4. doi: 10.1093/rpd/ncq051. Epub 2010 Feb 22.

DOI:10.1093/rpd/ncq051
PMID:20176733
Abstract

An abdomen phantom, containing an idealised fillable liver volume was developed. A fast settling gel was used to produce a row of simulated tumours as well as normal surrounding tissue, each of these components containing different concentrations of (18)F-FDG. The magnitude of the signal above normal tissue intensity as well as the noise was obtained after reconstructions with Ordered Subset expectation-maximization (OSEM) and various Gaussian smoothing filters. Signals derived by 'simulated intensity diffusion' agreed well with experimental results.

摘要

开发了一种腹部体模,其中包含理想化的可填充肝脏体积。使用一种快速凝固的凝胶来生成一排模拟肿瘤以及周围的正常组织,这些组件中的每一个都含有不同浓度的(18)F-FDG。在用有序子集期望最大化(OSEM)和各种高斯平滑滤波器进行重建后,获得了高于正常组织强度的信号幅度以及噪声。通过“模拟强度扩散”得出的信号与实验结果吻合良好。

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