From the University of Texas Southwestern Medical Center, Department of Obstetrics and Gynecology, Dallas, Texas.
Obstet Gynecol. 2010 Mar;115(3):605-608. doi: 10.1097/AOG.0b013e3181d068a3.
To examine whether preterm birth is related to the loop electrosurgical excision procedure (LEEP) itself or intrinsic to the women undergoing the procedure.
Rates of preterm birth, defined as births before 37 weeks of gestation, as well as causes were analyzed in women undergoing LEEP before or after an index pregnancy. These rates were compared with the general obstetric population.
A total of 241,701 women were delivered of singletons at Parkland Hospital between January 1992 and May 2008; of these women, 511 previously had undergone LEEP and another 842 underwent LEEP after the index pregnancy. When compared with the general obstetric population, no increased risk of preterm birth was observed for either group. This was true regardless of the reason for preterm birth. Likewise, there was no increased risk of delivery before 34 weeks or between 34 and 36 weeks of gestation.
No association was observed between LEEP and preterm birth in women undergoing the procedure before or after an index pregnancy.
探讨早产是否与环形电切术（LEEP）本身有关，还是与接受该手术的妇女本身有关。
分析了在指数妊娠之前或之后接受 LEEP 的妇女中早产（定义为妊娠 37 周之前分娩）的发生率以及原因。将这些比率与一般产科人群进行比较。
1992 年 1 月至 2008 年 5 月期间，共有 241701 名妇女在帕克兰医院分娩单胎；其中 511 名妇女先前接受过 LEEP，另有 842 名妇女在指数妊娠后接受了 LEEP。与一般产科人群相比，两组均未观察到早产风险增加。无论早产的原因是什么，这都是如此。同样，在妊娠 34 周之前或 34 至 36 周之间分娩的风险也没有增加。
在指数妊娠之前或之后接受 LEEP 的妇女中，LEEP 与早产之间没有关联。
