采用高效薄层色谱法测定原料药及药物制剂中的青蒿素。
Determination of Artemisinin in Bulk and Pharmaceutical Dosage Forms using HPTLC.
作者信息
Agarwal S P, Ali A, Dua Yashomati, Ahuja Shipra
机构信息
Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard University, New Delhi-110 062, India.
出版信息
Indian J Pharm Sci. 2009 Jan;71(1):98-100. doi: 10.4103/0250-474X.51948.
A new, simple, rapid, accurate and precise HPTLC method was developed. The detector response was linear for concentrations between 100-600 ng/spot (r =0.9931). The limits of detection and quantitation were 25 ng/spot and 75 ng/spot, respectively. The recovery study was carried out by standard addition method and was found to be 99.60+/-0.27. Statistical analysis proved that the method was precise, accurate and reproducible, and hence was suitable for the routine analysis of artemisinin.
开发了一种新的、简单、快速、准确且精密的高效薄层色谱法。检测器响应在100 - 600 ng/斑点浓度范围内呈线性（r = 0.9931）。检测限和定量限分别为25 ng/斑点和75 ng/斑点。采用标准加入法进行回收率研究，结果为99.60±0.27。统计分析证明该方法精密、准确且可重现，因此适用于青蒿素的常规分析。
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