一种用于高通量液滴界面双层（DIB）形成的微流控方法。
A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation.
机构信息
Department of Chemistry, Imperial College London, Exhibition Road, South Kensington, London, UKSW7 2AZ.
出版信息
Chem Commun (Camb). 2010 Mar 14;46(10):1620-2. doi: 10.1039/b924897h. Epub 2010 Jan 25.
We present a simple, automated method for high-throughput formation of droplet interface bilayers (DIBs) in a microfluidic device. We can form complex DIB networks that are able to fill predefined three dimensional architectures. Moreover, we demonstrate the flexibility of the system by using a variety of lipids including 1,2-diphytanoyl-sn-glycero-3-phosphocholine (DPhPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC).
我们提出了一种在微流控装置中形成高通量液滴界面双层（DIB）的简单、自动化方法。我们可以形成能够填充预定义三维结构的复杂 DIB 网络。此外，我们通过使用各种脂质（包括 1,2-二植烷酰基-sn-甘油-3-磷酸胆碱（DPhPC）和 1,2-二油酰基-sn-甘油-3-磷酸胆碱（DOPC））证明了该系统的灵活性。
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