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儿童腐蚀性食管狭窄的球囊扩张长期治疗。

Long-term management of corrosive esophageal stricture with balloon dilation in children.

机构信息

Department of Pediatric Surgery, Baskent University Faculty of Medicine, Ankara, Turkey.

出版信息

Surg Endosc. 2010 Sep;24(9):2287-92. doi: 10.1007/s00464-010-0953-x. Epub 2010 Feb 23.

Abstract

BACKGROUND AND PURPOSE

There are only a few studies focused on efficacy and safety of balloon dilation in corrosive esophageal stricture in children. The aim of this study is to assess the long-term clinical results of balloon dilation in the treatment of corrosive esophageal stricture in children.

MATERIALS AND METHODS

We retrospectively analyzed the management of 18 children (median age 3 years) who were treated with balloon dilation because of caustic esophageal stricture between January 2001 and December 2008.

RESULTS

A total of 295 sessions of balloon dilation were performed in all patients over an 8-year period. Technical success was achieved in all patients, whereas clinical success was achieved only in eight (44.4%) patients after first dilation. Eight (44.4%) of all patients showed recovery within the first year and another six (33.3%) patients recovered within 2 years. Esophageal perforation occurred in one (5%) patient, during one dilation session (0.33%). The average number of dilation sessions was 12.7, 2.8, and 1, respectively, in the first, second, and third year. There was significant difference between the mean number of dilation sessions in the first and second year, and second and third year (p < 0.01 and p = 0.043).

CONCLUSION

Short-segment esophageal strictures, improvement of food intake capacity, and increase in intervals of dilation sessions are good patient indicators. We suggest that esophageal balloon dilatation is a safe and effective method of treatment in caustic esophageal strictures and recommend that balloon dilation program be performed for at least 2 years before deciding that dilation has failed and preferring other treatment modalities which have higher risk of complications.

摘要

背景与目的

仅有少数研究关注于球囊扩张术治疗儿童腐蚀性食管狭窄的疗效和安全性。本研究旨在评估球囊扩张术治疗儿童腐蚀性食管狭窄的长期临床效果。

材料与方法

我们回顾性分析了 2001 年 1 月至 2008 年 12 月期间因腐蚀性食管狭窄接受球囊扩张治疗的 18 例儿童(中位年龄 3 岁)的治疗管理情况。

结果

在 8 年期间,所有患者共进行了 295 次球囊扩张。所有患者均达到技术成功,但首次扩张后仅 8 例(44.4%)患者达到临床成功。所有患者中有 8 例(44.4%)在第 1 年内恢复,另外 6 例(33.3%)在第 2 年内恢复。1 例(5%)患者在 1 次扩张过程中发生食管穿孔(0.33%)。第 1、2、3 年的平均扩张次数分别为 12.7、2.8 和 1 次。第 1 年和第 2 年、第 2 年和第 3 年的平均扩张次数之间存在显著差异(p<0.01 和 p=0.043)。

结论

短节段食管狭窄、进食能力改善和扩张间隔时间延长是患者的良好指标。我们认为,食管球囊扩张术是治疗腐蚀性食管狭窄的一种安全有效的方法,并建议在决定扩张治疗失败并选择其他并发症风险更高的治疗方式之前,至少进行 2 年的球囊扩张治疗计划。

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