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儿童腐蚀性物质摄入急性处理的标准化方案。

A standardised protocol for the acute management of corrosive ingestion in children.

作者信息

Baskin Didem, Urganci Nafiye, Abbasoğlu Latif, Alkim Canan, Yalçin Mehmet, Karadağ Cetin, Sever Nihat

机构信息

Department of Pediatric Surgery, Sisli Etfal Education and Research Hospital, Pehlivanyani Sok. 7/4, 34934 Mecidiyeköy, Istanbul, Turkey.

出版信息

Pediatr Surg Int. 2004 Dec;20(11-12):824-8. doi: 10.1007/s00383-004-1294-4. Epub 2004 Nov 9.

DOI:10.1007/s00383-004-1294-4
PMID:15538587
Abstract

Oesophageal strictures developing after caustic ingestion in children are a serious problem, and several protocols to prevent stricture formation have been proposed. A prospective clinical trial was conducted for preventing strictures in caustic oesophageal burns in a single clinic, and the results are presented. All children with caustic ingestion who had oesophagoscopy for diagnosing the severity of the burn were included in the study. Eighty-one children were included in the series, with ages ranging between 3 months and 12 years. The patients were given nothing by mouth until oesophagoscopy. IV fluids, broad-spectrum antibiotics, ranitidine, and a single-dose steroid were given. Oral burns were positive in 66 patients. Oesophagoscopy revealed a normal oesophagus in nine patients, grade 1 burn in 24, grade 2a in 21, grade 2b in 23, grade 3a in two, and grade 3b in one. Patients with grade 1 and 2a burns were discharged after oesophagoscopy. Patients with grade 2b and all grade 3 burns were given nothing by mouth for a week except water when swallowing their saliva, and were fed via total parenteral nutrition. After the 1st week, if there was no problem with swallowing, liquid foods were introduced. No intraluminal tubes were used. At the end of the 3rd week, a barium meal was administered and an upper gastrointestinal series taken. Dilatation was performed at 2-week intervals for strictures, which developed in one grade 2a patient, six grade 2b patients, and the grade 3b patient. Only one of these patients is currently on an oesophageal dilatation program. Limiting oral intake and avoiding foreign bodies in the oesophagus seem to provide a good success rate; however, further prospective studies are needed to decrease the incidence of corrosive oesophageal strictures.

摘要

儿童腐蚀性物质摄入后发生的食管狭窄是一个严重问题,已提出多种预防狭窄形成的方案。在一家诊所进行了一项预防腐蚀性食管烧伤后狭窄的前瞻性临床试验,并展示了结果。所有因腐蚀性物质摄入而接受食管镜检查以诊断烧伤严重程度的儿童均纳入研究。该系列纳入了81名儿童,年龄在3个月至12岁之间。在食管镜检查前患者禁食。给予静脉输液、广谱抗生素、雷尼替丁和一剂类固醇。66例患者有口腔烧伤。食管镜检查显示9例患者食管正常,24例为1级烧伤,21例为2a级,23例为2b级,2例为3a级,1例为3b级。1级和2a级烧伤患者在食管镜检查后出院。2b级和所有3级烧伤患者除吞咽唾液时可饮水外,一周内禁食,并通过全胃肠外营养进行喂养。第1周后,如果吞咽没有问题,开始引入流食。未使用腔内管。在第3周结束时,进行钡餐检查并拍摄上消化道造影。对1例2a级患者、6例2b级患者和3b级患者发生的狭窄每隔2周进行一次扩张。目前这些患者中只有1人在进行食管扩张治疗。限制经口摄入并避免食管内有异物似乎成功率较高;然而,需要进一步的前瞻性研究以降低腐蚀性食管狭窄的发生率。

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Risk factors for stricture development after caustic ingestion.腐蚀性物质摄入后狭窄形成的危险因素。
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