Pulmonology Department, Hospital General, La Raza National Medical Center, IMSS, México City, Mexico.
Sleep Breath. 2011 Jan;15(1):113-9. doi: 10.1007/s11325-010-0333-8. Epub 2010 Feb 23.
To develop and validate a questionnaire to identify patients with obstructive sleep apnea (OSA) in Mexican population.
We performed a cross-sectional study to develop and validate an instrument in Spanish language, consistent in an 18-item questionnaire. We enrolled patients seen from July 2008 to August 2009. We evaluated the internal consistency with the Kuder Richardson coefficient, a value greater than 0.70 was considered a good index correlation. Sensitivity, specificity, and positive and negative predictive factor was obtained with standard methods by comparison with polysomnographic results. Validity of Mexican questionnaire at baseline and follow-up was assessed using Pearson correlations coefficient.
We enrolled 100 patients. The initial pool comprised 25 items, four items were considered confusing and they were omitted; then, a preliminary questionnaire comprising 21 items was obtained, and three items were removed by presenting a response rate lesser than 90%, yielding a total of 18 items for the final questionnaire. This evaluation was performed stratifying in groups related to severity of illness. Snoring was the question with the greatest sensitivity to detect OSA; and obesity class I was the criteria with greatest specificity to detect OSA.
The screening tool proposed in this study has the advantages of being quick, inexpensive, easy to apply and reproducible, and the result has reliability with acceptable sensitivity; this is a symptom-based questionnaire with good predictive ability and it will avoid unnecessary sleep studies in the subjects who are not at high risk for having OSA.
开发并验证一种适用于墨西哥人群的识别阻塞性睡眠呼吸暂停（OSA）患者的问卷。
我们进行了一项横断面研究，以开发和验证一种西班牙语的工具，该工具由 18 个项目组成的问卷。我们招募了 2008 年 7 月至 2009 年 8 月就诊的患者。我们用 Kuder Richardson 系数评估内部一致性，大于 0.70 的值被认为是一个很好的相关指数。通过与多导睡眠图结果比较，采用标准方法获得敏感性、特异性、阳性和阴性预测因子。使用 Pearson 相关系数评估墨西哥问卷在基线和随访时的有效性。
我们共招募了 100 名患者。最初的项目池包含 25 个项目，其中 4 个项目被认为令人困惑而被删除；然后，获得了一个由 21 个项目组成的初步问卷，有 3 个项目因响应率小于 90%而被删除，最终得到了总共 18 个项目的最终问卷。该评估是在与疾病严重程度相关的分组中进行的。打鼾是检测 OSA 最敏感的问题；肥胖 I 级是检测 OSA 特异性最高的标准。
本研究提出的筛查工具具有快速、经济、易于应用和可重复的优点，并且结果具有可接受的敏感性和可靠性；这是一种基于症状的问卷，具有良好的预测能力，可以避免对那些患 OSA 风险不高的患者进行不必要的睡眠研究。
