Daltro Carla H da Cunha, Fontes Francisco H de O, Santos-Jesus Rogério, Gregorio Paloma Baiardi, Araújo Leila Maria Batista
Universidade Federal da Bahia, Real Sociedade de Beneficência Portuguesa, Hospital Português, Salvador, BA.
Arq Bras Endocrinol Metabol. 2006 Feb;50(1):74-81. doi: 10.1590/s0004-27302006000100011. Epub 2006 Apr 17.
Obstructive sleep apnea and hypopnea syndrome (OSAHS) has been the focus of extensive research because of its association with neurocognitive and cardiovascular complications. The aim of this study was to evaluate the frequency and association between OSAHS and the class of obesity, gender and age in outpatients referred to a sleep laboratory. We selected 1,595 patients, 71.7% male. Mean +/- SD age was 46.7 +/- 11.7 years, BMI was 28.1 +/- 5.1 kg/m2 and AIH was 13.9 +/- 15.5 events/ hour of sleep. The patients were considered apneic when the apnea-hypopnea index (AHI) was > 5 events/hour of sleep; OSAHS was present in: (1) 71.1% of men and 50.3% of women (p < 0.001); (2) in 45.3% of patients with normal BMI, in 64.3% of those overweighed and in 80% of obese (p < 0.001). According to age, 61.2% with age < 55 were apneic, as well as 78% of those with age > 55 years old (p < 0.001). We concluded that OSAHS was directly and strongly associated to the male gender, obesity class and to aging.
阻塞性睡眠呼吸暂停低通气综合征（OSAHS）因其与神经认知及心血管并发症相关，一直是广泛研究的焦点。本研究旨在评估在转诊至睡眠实验室的门诊患者中，OSAHS的发生率及其与肥胖类型、性别和年龄之间的关联。我们选取了1595例患者，其中男性占71.7%。平均年龄±标准差为46.7±11.7岁，体重指数（BMI）为28.1±5.1kg/m²，呼吸暂停低通气指数（AHI）为13.9±15.5次/小时睡眠。当呼吸暂停低通气指数（AHI）>5次/小时睡眠时，患者被视为呼吸暂停；OSAHS的发生率如下：（1）男性为71.1%，女性为50.3%（p<0.001）；（2）正常BMI患者中为45.3%，超重患者中为64.3%，肥胖患者中为80%（p<0.001）。按年龄划分，年龄<55岁的患者中有61.2%存在呼吸暂停，年龄>55岁的患者中有78%存在呼吸暂停（p<0.001）。我们得出结论，OSAHS与男性性别、肥胖类型及衰老直接且密切相关。
