Kontoangelos Konstantinos, Vaidakis Nikolaos, Zervas Ioannis, Thomadaki Olga, Christaki Smaragda, Stavrianeas Nikolaos G, Papadimitriou George N
Athens University Medical School, 1st Department of Psychiatry, Eginition Hospital, 74 Vas Sofias Avenue, 11528, Athens, Greece.
Cases J. 2010 Feb 23;3:69. doi: 10.1186/1757-1626-3-69.
This case report documents the effectiveness of inositol treatment on a chronic patient with bipolar disorder I and severe psoriasis. Her lithium treatment was discontinued due to psoriasis exacerbation and inositol was administered. The remarked positive effect of inositol was noted on her stable mood during the last 4 years, the absence of psoriatic lesions, which lead to an improved quality of life of the patient.
A 62-year-old female Caucasian patient suffering from bipolar disorder, since the age of 32, presenting manic episodes when without lithium treatment. Lithium treatment caused severe exacerbation of psoriasis and was discontinued while anti-psoriatic treatment had no effect. The last 4 years the patient receives 3 gr per day of inositol alone and her mood has been stabilized while there is also a remarkable improvement on her psoriatic lesions.
Taking into consideration the course of her bipolar disorder when lithium was discontinued previously we consider that the 4 years of follow up assessments of this patient as a satisfactory time period for concluding that inositol has been a very effective treatment, replacing lithium, for mood stabilization and psoriasis.
本病例报告记录了肌醇治疗一名患有I型双相情感障碍和重度银屑病的慢性病患者的有效性。由于银屑病加重，她停用了锂盐治疗并开始使用肌醇。在过去4年中，肌醇对她的情绪稳定产生了显著的积极影响，银屑病皮损消失，患者生活质量得到改善。
一名62岁的白种女性患者，自32岁起患有双相情感障碍，在未使用锂盐治疗时出现躁狂发作。锂盐治疗导致银屑病严重加重，停药后抗银屑病治疗无效。在过去4年里，患者每天单独服用3克肌醇，情绪稳定，银屑病皮损也有显著改善。
考虑到该患者之前停用锂盐时双相情感障碍的病程，我们认为对该患者进行4年的随访评估是一个令人满意的时间段，可以得出结论：肌醇是一种非常有效的治疗方法，可替代锂盐用于稳定情绪和治疗银屑病。
