光转导：密切关注酸不稳定的瞬时受体电位通道。

Phototransduction: keep an eye out for acid-labile TRPs.

机构信息

Ludwig-Maximilians-Universitaet Muenchen, Walther-Straub-Institut of Pharmacology and Toxicology, Goethestr. 33, 80336 Munich, Germany.

出版信息

Curr Biol. 2010 Feb 23;20(4):R149-52. doi: 10.1016/j.cub.2010.01.013.

DOI:10.1016/j.cub.2010.01.013

PMID:20178757

Abstract

Our mechanistic understanding of phototransduction in the Drosophila eye is still rudimentary. Recent work demonstrates that a combination of phosphoinositide depletion and microvillar acidification is sufficient to activate light-sensitive TRPC channels.

摘要

我们对果蝇眼睛光转导的机制理解仍然很初步。最近的工作表明，磷酸肌醇耗竭和微绒毛酸化的组合足以激活光敏感的 TRPC 通道。