Scientific Institute IRCCS E. Medea, Bioinformatics, Via don L. Monza 20, 23842 Bosisio Parini (LC), Italy.
Microbes Infect. 2010 Jun;12(6):421-7. doi: 10.1016/j.micinf.2010.02.002. Epub 2010 Feb 21.
The hygiene hypothesis relies on the assumption that humans have adapted to a pathogen-rich environment that no longer exists in industrialized societies. Recent advances in molecular immunology and population genetics allow deeper insight into the evolution and co-evolution of host-pathogen interactions and, therefore, into the foundations of the hygiene hypothesis.
卫生假说依赖于这样一种假设，即人类已经适应了一种不再存在于工业化社会中的病原体丰富的环境。分子免疫学和群体遗传学的最新进展使我们能够更深入地了解宿主-病原体相互作用的进化和共同进化，从而深入了解卫生假说的基础。
