Biesecker Pediatric Liver Center, Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
J Pediatr Gastroenterol Nutr. 2010 Apr;50(4):417-21. doi: 10.1097/MPG.0b013e3181b99cba.
The objectives of the present study were to assess the prevalence, frequency and type of complementary and alternative medicine (CAM) used by children with chronic viral hepatitis infection, and to determine correlates of use and estimates of nondisclosure regarding CAM use.
In this cross-sectional pilot study, families of 68 children receiving care for chronic viral hepatitis at a tertiary medical center were administered a survey regarding use of CAM.
Forty-six percent of these families reported using CAM for their child at least once since diagnosis with chronic viral hepatitis and 31% used CAM monthly or more frequently. Of all of the CAM therapies, biologically based products such as herbals and dietary supplements were used most often. Use of CAM was independently associated with the current or previous use of antiviral medications for viral hepatitis, parent's use of CAM, and child having a nonliver comorbidity. Rates of physician nondisclosure regarding CAM use were >60%.
This is the first report of CAM use in children with chronic viral hepatitis. Use of CAM in this population is common, and despite published adult reports, there is infrequent dialogue between patients and pediatric health care providers regarding use of CAM.
本研究旨在评估慢性病毒性肝炎感染儿童使用补充和替代医学（CAM）的流行率、频率和类型，并确定使用的相关性以及对 CAM 使用的隐瞒估计。
在这项横断面试点研究中，为在三级医疗中心接受慢性病毒性肝炎治疗的 68 名儿童的家庭管理了一项关于 CAM 使用的调查。
这些家庭中有 46%报告自诊断为慢性病毒性肝炎以来至少为孩子使用过一次 CAM，31%每月或更频繁地使用 CAM。在所有的 CAM 治疗中，基于生物的产品，如草药和膳食补充剂，使用最为广泛。CAM 的使用与目前或以前使用抗病毒药物治疗病毒性肝炎、父母使用 CAM 和儿童患有非肝脏合并症独立相关。关于 CAM 使用的医生隐瞒率>60%。
这是第一篇关于慢性病毒性肝炎儿童 CAM 使用的报告。在该人群中，CAM 的使用很常见，尽管有已发表的成人报告，但患者和儿科医疗保健提供者之间很少就 CAM 的使用进行对话。
