Nowack Rainer, Ballé Christoph, Birnkammer Franz, Koch Wolfgang, Sessler Roland, Birck Rainer
Center for Nephrology and Dialysis Lindau/Bodensee, Lindau, Germany.
J Ren Nutr. 2009 May;19(3):211-9. doi: 10.1053/j.jrn.2008.08.008. Epub 2009 Feb 28.
Complementary and alternative medicine (CAM) is frequently used in the general population, yet scant data are available regarding the prevalence of these medications in patients with end-stage renal disease (ESRD).
To survey patients with ESRD regarding their use of CAM and health foods.
Consecutive patients treated with dialysis or renal transplantation for ESRD were approached by nephrologists of 5 renal centers to report their usage of and knowledge on CAM and health foods by answering a questionnaire. Of 180 approached patients, 164 returned completed questionnaires for analysis.
Fifty-seven percent of dialysis patients and 49% of transplant patients reported to be regular CAM-consumers. CAM consumption was positively associated with female sex and negatively with diabetes as comorbidity. Forty-one different CAM products had been named, with mineral supplements and vitamins ranking first. Besides CAM, many renal patients had regularly consumed herbal teas and citrus-juices (50% and 35%, respectively). Close to 40% of the documented CAM/health food consumptions have potential risks for patients because of constituents that either accumulate in renal failure or interact with pharmaceutical medication. However, only about 50% of dialysis patients, but 73% of transplant patients used to inform their physicians about CAM consumption (P = .005). Awareness about interaction risks linked to CAM was especially low in dialysis patients when compared to transplant patients (39% versus 78%, P < .0001) and increased when physicians had routinely questioned patients about their CAM consumption. Currently, however, patients reported that only a minority of physicians had taken an active interest into consumption of these substances.
Consumption of CAM and health food is common among renal patients. Physicians are currently not adequately informed about CAM consumption by their patients. Because many products are at risk to either accumulate or cause interactions with medication, physicians should take an active role to inform themselves.
补充和替代医学(CAM)在普通人群中使用频繁,但关于这些药物在终末期肾病(ESRD)患者中的流行情况,可用数据却很少。
调查ESRD患者对CAM和健康食品的使用情况。
5个肾脏中心的肾病科医生对因ESRD接受透析或肾移植治疗的连续患者进行调查,让他们通过回答问卷来报告对CAM和健康食品的使用情况及了解程度。在180名接受调查的患者中,164名返回了完整问卷以供分析。
57%的透析患者和49%的移植患者报告称经常使用CAM。CAM的使用与女性性别呈正相关,与糖尿病作为合并症呈负相关。共提及了41种不同的CAM产品,其中矿物质补充剂和维生素位居首位。除了CAM,许多肾病患者还经常饮用花草茶和柑橘汁(分别为50%和35%)。记录在案的CAM/健康食品消费中,近40%因含有在肾衰竭时会蓄积或与药物相互作用的成分,对患者存在潜在风险。然而,只有约50%的透析患者,但73%的移植患者会告知医生他们使用CAM的情况(P = 0.005)。与移植患者相比,透析患者对CAM相关相互作用风险的知晓率特别低(39%对78%,P < 0.0001),当医生常规询问患者CAM的使用情况时,知晓率会提高。然而目前,患者报告称只有少数医生积极关注这些物质的消费情况。
CAM和健康食品在肾病患者中使用普遍。目前医生对患者使用CAM的情况了解不足。由于许多产品存在蓄积风险或会与药物产生相互作用,医生应积极了解相关情况。