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[溃疡性结肠炎与精神分裂症:偶然关联还是病因学联系?]

[Ulcerative colitis and schizophrenia: fortuitous association or etiopathogenic link?].

作者信息

Ennaifer R, Rafrafi R, Mouelhi L, Houissa F, Bouzaidi S, Trabelsi S, El Hechmi Z, Najjar T

机构信息

Service de Gastro-entirologie, Hôpital Charles Nicolle, Tunis, Tunisie.

出版信息

Tunis Med. 2009 Aug;87(8):531-3.

PMID:20180358
Abstract

BACKGROUND

Ulcerative colitis is a chronic inflammatory bowel disease with multiple pathogenic factors. Psychiatric disorder have frequently been associated to ulcerative colitis, the most frequent being depression and anxiety, whereas schizophrenia is unusual.

AIM

Report a new case of ulcerative colitis associated topsychiatric disorder.

CASE-REPORT: We report the case of a 42-year-old woman with ulcerative colitis associated with schizophrenia. Although the two diagnoses were concomitant, on questioning, she revealed that digestive symptoms began before psychiatric disorders.

CONCLUSION

Few cases of schizophrenia associated with ulcerative colitis have been reported in the literature. We discuss epidemiological, etiopathogenic and therapeutic links between the two diseases.

摘要

背景

溃疡性结肠炎是一种具有多种致病因素的慢性炎症性肠病。精神障碍常与溃疡性结肠炎相关,最常见的是抑郁和焦虑,而精神分裂症则不常见。

目的

报告一例与精神障碍相关的溃疡性结肠炎新病例。

病例报告

我们报告了一例42岁患有溃疡性结肠炎并伴有精神分裂症的女性病例。尽管这两种诊断是同时出现的,但经询问,她透露消化症状在精神障碍之前就已出现。

结论

文献中报道的溃疡性结肠炎合并精神分裂症的病例很少。我们讨论了这两种疾病之间的流行病学、病因和治疗方面的联系。

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