Jerraya Hichem, Bel Haj Salah Riadh, Ben Mena Khalil, Haouet Karim, Zaouche Abdeljelil
Surgical unit A, Charles Nicolle Hospital, Tunis, Tunisia.
Tunis Med. 2009 Sep;87(9):556-9.
Gastrointestinal stromal tumours are a large category of primary no epithelial neoplasms of the digestive tract. The localization of stromal tumours in the ampulla of Vater (STAV) is very rare.
The aim of this study was to describe clinical, endoscopic and therapeutic particularities of STAV.
We reported a new case and we carried out an extensive electronic search for the relevant literature using Medline. Key words used were "ampulla of Vater" and "Gastrointestinal stromal tumor" and "CD 117". With our case, we collected seven other cases in the literature.
The analysis of the sample of these eight cases leads us to propose the following conclusions. STAV is a tumor of adult after the age of fifty. There is no specific symptomatology. Gastroduodenal endoscopy with biopsies and immunoassaying allows positive preoperative diagnosis in the 5 cases. Treatment should be duodenopancreatectomy since the tumor is often malignant (5 cases).
胃肠道间质瘤是一大类消化道原发性非上皮性肿瘤。位于十二指肠乳头的间质瘤（STAV）非常罕见。
本研究旨在描述STAV的临床、内镜及治疗特点。
我们报告了1例新病例，并使用Medline对相关文献进行了广泛的电子检索。使用的关键词为“十二指肠乳头”、“胃肠道间质瘤”和“CD 117”。结合我们的病例，我们收集了文献中的其他7例病例。
对这8例病例样本的分析使我们得出以下结论。STAV是一种50岁以后的成人肿瘤。没有特异性症状。通过胃十二指肠内镜检查、活检及免疫测定，5例患者术前得到阳性诊断。由于肿瘤常为恶性（5例），治疗应行胰十二指肠切除术。
