Endocrinology Clinic, Hippokration Hospital, Thessaloniki, Greece.
Curr Vasc Pharmacol. 2010 Sep;8(5):646-60. doi: 10.2174/157016110792006996.
Hypertension is a major contributor to vascular morbidity and mortality. Endocrine hypertension (EH) refers to secondary hypertension caused by specific endocrine abnormalities. The significance of EH is that the identification of the underlying disorder and its management may lead to partial or complete normalization of blood pressure. When EH is suspected thorough investigation with biochemical and imaging testing are necessary to establish or exclude mineralocorticoid, catecholamine, glucocorticoid, thyroid, parathyroid or growth hormone disorders as well as rare hereditary syndromes. In addition, it is important to differentiate benign from malignant tumors. The present review provides an update on the pathophysiology and clinical presentation of EH. We also discuss the diagnostic work-ups and therapeutic strategies.
高血压是血管发病率和死亡率的主要原因。内分泌性高血压（EH）是指由特定内分泌异常引起的继发性高血压。EH 的重要性在于，确定潜在疾病及其管理可能导致血压部分或完全正常化。当怀疑 EH 时，需要进行生化和影像学检查以确定或排除醛固酮、儿茶酚胺、糖皮质激素、甲状腺、甲状旁腺或生长激素疾病以及罕见的遗传性综合征。此外，区分良性和恶性肿瘤也很重要。本综述提供了 EH 的病理生理学和临床表现的最新信息。我们还讨论了诊断方法和治疗策略。
