Division of Infection, Inflammation and Immunity, University of Southampton School of Medicine, Southampton, UK.
Allergy. 2010 Aug;65(8):933-45. doi: 10.1111/j.1398-9995.2010.02342.x. Epub 2010 Feb 22.
Food allergy affects 6% of children but there is no cure, and strict avoidance of index allergens along with immediate access to rescue medication is the current best management. With specialist care, morbidity from food allergy in children is generally low, and mortality is very rare. However, there is strong evidence that food allergy and food hypersensitivity has an impact on psychological distress and on the quality of life (QoL) of children and adolescents, as well as their families. Until recently, the measurement of QoL in allergic children has proved difficult because of the lack of investigative tools available. New instruments for assessing QoL in food allergic children have recently been developed and validated, which should provide further insights into the problems these children encounter and will enable us to measure the effects of interventions in patients. This review examines the published impact of food allergy on affected children, adolescents and their families. It considers influences such as gender, age, disease severity, co-existing allergies and external influences, and examines how these may impact on allergy-related QoL and psychological distress including anxiety and depression. Implications of the impact are considered alongside avenues for future research.
食物过敏影响 6%的儿童，但目前尚无治愈方法，严格避免过敏原和及时使用急救药物是目前的最佳治疗方法。在专业护理下，儿童食物过敏的发病率通常较低，死亡率非常罕见。然而，有强有力的证据表明，食物过敏和食物过敏反应会对儿童和青少年及其家庭的心理困扰和生活质量（QoL）产生影响。直到最近，由于缺乏可用的研究工具，证明测量过敏儿童的 QoL 具有一定难度。最近开发并验证了用于评估食物过敏儿童 QoL 的新工具，这将有助于深入了解这些儿童所面临的问题，并使我们能够衡量患者干预措施的效果。这篇综述考察了食物过敏对受影响的儿童、青少年及其家庭的已发表影响。它考虑了性别、年龄、疾病严重程度、共存过敏和外部影响等因素，并探讨了这些因素如何影响与过敏相关的 QoL 和心理困扰，包括焦虑和抑郁。还考虑了影响的影响以及未来研究的方向。
