Camuglia Jayne E, Beltz Jacqueline E, Khurana Kavita, Hall Anthony Jh
Department of Ophthalmology, The Alfred Hospital, Commercial Road, Prahran, Melbourne, Victoria 3004, Australia.
Cases J. 2010 Jan 12;3(1):17. doi: 10.1186/1757-1626-3-17.
The vascular complications of herpes zoster are well recognised, however, there are few reports of central retinal artery occlusion. Central retinal artery occlusion following herpes zoster ophthalmicus is poorly recognised. This is likely due to the difficulties in obtaining tissue for histopathology to establish causality. We report a case of central retinal artery occlusion and complete internal carotid artery occlusion following herpes zoster ophthalmicus.
A 44 year old Caucasian female presented with sudden painless loss of vision in her right eye on a background of chronic lymphocytic leukaemia and right sided herpes zoster ophthalmicus. She was initially treated with steroids and antivirals for an underlying presumed vasculitic cause, but review at 24 hours demonstrated a right central retinal artery occlusion. Embolic screen identified complete occlusion of the right internal carotid artery. She was treated with oral antiviral medication for three weeks but had no visual recovery.
This case highlights an uncommon cause of acute visual loss. We propose that the underlying small and large vessel occlusion in this patient was due to herpes zoster related vasculopathy. A review of the literature is presented to trace the historical perspective of herpes zoster related vasculopathy.
带状疱疹的血管并发症已得到充分认识,然而,关于视网膜中央动脉阻塞的报道却很少。眼部带状疱疹后发生视网膜中央动脉阻塞的情况鲜为人知。这可能是由于难以获取组织进行组织病理学检查以确定因果关系。我们报告一例眼部带状疱疹后发生视网膜中央动脉阻塞及颈内动脉完全阻塞的病例。
一名44岁的白种女性,在患有慢性淋巴细胞白血病和右侧眼部带状疱疹的背景下,右眼突然无痛性视力丧失。她最初因潜在的血管炎病因接受了类固醇和抗病毒药物治疗,但24小时后的复查显示右侧视网膜中央动脉阻塞。栓子筛查发现右侧颈内动脉完全阻塞。她接受了三周的口服抗病毒药物治疗,但视力未恢复。
本病例突出了急性视力丧失的一种罕见病因。我们认为该患者潜在的小血管和大血管阻塞是由带状疱疹相关血管病变引起的。本文回顾了文献以追溯带状疱疹相关血管病变的历史观点。