Department of Medicine, Sinai Grace Hospital/Detroit Medical Center, Detroit, Michigan, USA.
Diagn Pathol. 2010 Jan 29;5:11. doi: 10.1186/1746-1596-5-11.
Carcinosarcoma of the lung is a malignant tumor composed of a mixture of carcinoma and sarcoma elements. The carcinomatous component is most commonly squamous followed by adenocarcinoma. The sarcomatous component commonly comprises the bulk of the tumor and shows poorly differentiated spindle cell features. Foci of differentiated sarcomatous elements such as chondrosarcoma and osteosarcoma may be seen. Aspergillus pneumonia is the most common form of invasive aspergillosis and occurs mainly in patients with malignancy, immunocompromising or debilitating diseases. Patients with Aspergillus pneumonia present with fever, cough, chest pain and occasionally hemoptysis. Tissue examination is the most reliable method for diagnosis, and mortality rate is high.We describe a case of primary carcinosarcoma of the lung concurrently occurring with invasive pulmonary aspergillosis in a 66-year old patient.
肺的癌肉瘤是一种由癌和肉瘤成分混合组成的恶性肿瘤。癌性成分最常见的是鳞状细胞癌，其次是腺癌。肉瘤成分通常构成肿瘤的大部分，并表现出低分化梭形细胞特征。可能会看到分化良好的肉瘤成分，如软骨肉瘤和骨肉瘤的病灶。曲霉菌肺炎是侵袭性曲霉菌病最常见的形式，主要发生在恶性肿瘤、免疫抑制或虚弱的患者中。曲霉菌肺炎患者表现为发热、咳嗽、胸痛，偶尔咯血。组织检查是诊断的最可靠方法，死亡率很高。我们描述了一例 66 岁患者同时发生原发性肺癌肉瘤和侵袭性肺曲霉菌病的病例。
