Department of Respiratory Medicine, Changhai Affiliated Hospital of the Second Military Medical University, Shanghai 200433, China.
Diagn Pathol. 2013 Oct 21;8:174. doi: 10.1186/1746-1596-8-174.
As acute inhalational injury is an uncommon presentation to most institutions, a standard approach to its assessment and management, especially using flexible bronchoscopy, has not received significant attention.
The objective of this study is to evaluate the value of using flexible bronchoscopy as part of the evaluation and management of patients with inhalational lung injury. Twenty-three cases of inhalational lung injury were treated in our three hospitals after a fire in a residential building. The twenty cases that underwent bronchoscopy as part of their management are included in this analysis. After admission, the first bronchoscopy was conducted within 18-72 hours post inhalational injury. G2-level patients were reexamined 24 hours after the first bronchoscopy, while G1-level patients were reexamined 72 hours later. Subsequently, all patients were re-examined every 2-3 days until recovered or until only tunica mucosa bronchi congestion was identified by bronchoscopy.
Twenty patients had airway injury diagnosed by bronchoscopy including burns to the larynx and glottis or large airways. Bronchoscopic classification of the inhalation injury was performed, identifying 12 cases of grade G1 changes and 8 cases of grade G2. The airway injury in the 12 cases of grade G1 patients demonstrated recovery in 2-8 days, in the airway injury of the 8 cases of grade G2 patients had a prolonged recovery with airway injury improving in 6-21 days averaged. The difference in recovery time between the two groups was significant (P <0.05).
The use of flexible bronchoscopy has great value in the diagnosis of inhalational injury without any complications. Its use should be incorporated into clinical practice.
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由于急性吸入性损伤在大多数医疗机构中较为少见,因此针对其评估和管理的标准方法,尤其是使用纤维支气管镜,尚未得到广泛关注。
本研究旨在评估纤维支气管镜检查在吸入性肺损伤患者评估和管理中的应用价值。在一栋居民楼火灾后,我们医院共收治了 23 例吸入性肺损伤患者,其中 20 例行支气管镜检查的患者纳入本分析。患者吸入损伤后 18-72 小时内行首次纤维支气管镜检查,G2 级患者于首次检查后 24 小时复查,G1 级患者于 72 小时复查,此后所有患者每 2-3 天复查一次,直至患者恢复或支气管镜检查仅发现黏膜支气管充血。
20 例患者经纤维支气管镜检查发现气道损伤,包括喉和声带烧伤或大气道烧伤。对吸入性损伤进行支气管镜分类,其中 12 例为 G1 级改变,8 例为 G2 级。12 例 G1 级患者的气道损伤在 2-8 天内恢复,8 例 G2 级患者的气道损伤恢复时间延长,气道损伤在 6-21 天内改善,平均为 14 天。两组患者的恢复时间差异有统计学意义(P<0.05)。
纤维支气管镜检查在诊断吸入性损伤方面具有重要价值,且无任何并发症。应将其纳入临床实践。
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