Danis Ramazan, Akbulut Sami, Altintas Abdullah, Ozmen Sehmus, Ozmen Cihan Akgul
Department of Surgery, Diyarbakir Education and Research Hospital, 21400, Diyarbakir, Turkey.
J Med Case Rep. 2010 Feb 8;4:46. doi: 10.1186/1752-1947-4-46.
Eosinophilic fasciitis is an uncommon disorder with unknown etiology and a poorly understood pathogenesis. We present the cases of two patients with eosinophilic fasciitis with unusual presentation, and describe the clinical characteristics and laboratory findings related to them.
The first case involves a 29-year-old Turkish man admitted with pain, edema and induration of his right-upper and left-lower limbs. Unilateral edema and stiffness with prominent pretibial edema was noted upon physical examination. A high eosinophil count was found on the peripheral smear. The second case involves a 63-year-old Turkish man who had pain, edema, erythema, and itching on his upper and lower extremities, which developed after strenuous physical activity. He had cervical lymphadenopathy and polyarthritis upon physical examination, and rheumatoid factor and antinuclear antibody upon laboratory examination.
Eosinophilic fasciitis can present with various symptoms. When patients exhibit eosinophilia, arthralgia and myalgia, eosinophilic fasciitis should be considered as a possible diagnosis.
嗜酸性筋膜炎是一种病因不明、发病机制尚不清楚的罕见疾病。我们报告两例表现不寻常的嗜酸性筋膜炎病例，并描述与之相关的临床特征和实验室检查结果。
第一例患者为一名29岁的土耳其男性，因右上肢和左下肢疼痛、水肿及硬结入院。体格检查发现单侧水肿和僵硬，胫前水肿明显。外周血涂片显示嗜酸性粒细胞计数升高。第二例患者为一名63岁的土耳其男性，在剧烈体力活动后出现上下肢疼痛、水肿、红斑和瘙痒。体格检查发现颈部淋巴结肿大和多关节炎，实验室检查发现类风湿因子和抗核抗体阳性。
嗜酸性筋膜炎可表现出多种症状。当患者出现嗜酸性粒细胞增多、关节痛和肌痛时，应考虑嗜酸性筋膜炎作为可能的诊断。
