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Unexpected aflatoxin exposure in a woman in northern Italy: a case report.意大利北部一名女性意外接触黄曲霉毒素:病例报告。
Cases J. 2009 Sep 17;2:7736. doi: 10.1186/1757-1626-0002-0000007736.
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本文引用的文献

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Investigation of acute effects of aflatoxin on rat proximal and distal colon spontaneous contractions.黄曲霉毒素对大鼠近端和远端结肠自发收缩的急性影响研究。
Food Chem Toxicol. 2008 Aug;46(8):2876-80. doi: 10.1016/j.fct.2008.05.028. Epub 2008 Jun 2.
2
Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1.伞形科蔬菜成分可抑制人细胞色素P-450 1A2(hCYP1A2)活性以及hCYP1A2介导的黄曲霉毒素B1的致突变性。
Food Chem Toxicol. 2006 Sep;44(9):1474-84. doi: 10.1016/j.fct.2006.04.010. Epub 2006 Apr 27.
3
Role of metabolism and viruses in aflatoxin-induced liver cancer.代谢与病毒在黄曲霉毒素诱发肝癌中的作用。
Toxicol Appl Pharmacol. 2005 Aug 7;206(2):131-7. doi: 10.1016/j.taap.2004.09.020.
4
Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions.发展中国家的人类黄曲霉毒素中毒:毒理学、暴露、潜在健康后果及干预措施综述
Am J Clin Nutr. 2004 Nov;80(5):1106-22. doi: 10.1093/ajcn/80.5.1106.
5
Chemoprevention of hepatocellular carcinoma in aflatoxin endemic areas.黄曲霉毒素流行地区肝细胞癌的化学预防
Gastroenterology. 2004 Nov;127(5 Suppl 1):S310-8. doi: 10.1053/j.gastro.2004.09.046.
6
Mycotoxins.霉菌毒素
Clin Microbiol Rev. 2003 Jul;16(3):497-516. doi: 10.1128/CMR.16.3.497-516.2003.
7
Acute effects of aflatoxins on guinea pig isolated ileum.黄曲霉毒素对豚鼠离体回肠的急性作用。
Toxicol In Vitro. 2002 Oct;16(5):525-9. doi: 10.1016/s0887-2333(02)00049-8.
8
Toxic effects of mycotoxins in humans.霉菌毒素对人类的毒性作用。
Bull World Health Organ. 1999;77(9):754-66.
9
Attempted suicide with purified aflatoxin.
Lancet. 1980 May 31;1(8179):1198-9. doi: 10.1016/s0140-6736(80)91665-7.
10
[The significance of mycotoxin assimilation for meat animals].[霉菌毒素同化作用对肉用动物的意义]
Dtsch Tierarztl Wochenschr. 1989 Jul-Aug;96(7):360-3.

意大利北部一名女性意外接触黄曲霉毒素:病例报告。

Unexpected aflatoxin exposure in a woman in northern Italy: a case report.

作者信息

Perduri Riccardo, Gobba Stefania

机构信息

Department of Public Health Sciences, Postgraduate School of Occupational Medicine, Chair of Occupational Medicine, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena, Italy.

出版信息

Cases J. 2009 Sep 17;2:7736. doi: 10.1186/1757-1626-0002-0000007736.

DOI:10.1186/1757-1626-0002-0000007736
PMID:20181196
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2827137/
Abstract

INTRODUCTION

In well-developed countries scant attention is currently devoted to the risk of unknown exposure to aflatoxins, highly toxic and carcinogenic compounds. Nevertheless, unexpected ingestion of foods contaminated by these toxins can occasionally occur virtually worldwide.

CASE PRESENTATION

A 38-year-old woman living in Northern Italy developed unexplained abdominal symptoms after ingestion of aflatoxin-contaminated meat. The possible relation between symptoms and aflatoxins ingestion, the potential risk of hepatocellular carcinoma and the medical management of the case are discussed.

CONCLUSION

In well-developed countries aflatoxins exposure should be considered in case of unexplained abdominal symptoms. Cancer risk cannot be assessed, nevertheless individual counselling and periodical medical examinations are recommended.

摘要

引言

在发达国家,目前人们很少关注未知黄曲霉毒素暴露的风险,黄曲霉毒素是剧毒且致癌的化合物。然而,实际上在全球范围内偶尔会意外摄入被这些毒素污染的食物。

病例介绍

一名居住在意大利北部的38岁女性在摄入受黄曲霉毒素污染的肉类后出现不明原因的腹部症状。讨论了症状与黄曲霉毒素摄入之间的可能关系、肝细胞癌的潜在风险以及该病例的医疗处理。

结论

在发达国家,如果出现不明原因的腹部症状,应考虑黄曲霉毒素暴露。虽然无法评估癌症风险,但建议进行个体咨询和定期体检。