Papandreou Christos, Skopelitou Antigoni, Kappes George, Daouaher Housam
Department of Urology, General Hospital of Arta, Greece.
J Med Case Rep. 2010 Feb 24;4:70. doi: 10.1186/1752-1947-4-70.
Primary osteosarcoma is one of the rare tumors affecting the urinary bladder. The occurrence of osteosarcoma in a patient with a long history of transitional cell carcinoma of the bladder is even more uncommon.
We present the case of a 74-year-old Greek man who was diagnosed with osteosarcoma 10 years after he had been diagnosed with transitional cell carcinoma of the bladder from which he had been free from recurrences for the past three years. Our patient was treated for the osteosarcoma with transurethral resection of bladder tumor and external beam radiation therapy. He died eight months after the diagnosis, suffering poor quality of life in the last months.
Osteosarcoma of the bladder has a dismal prognosis. External beam radiation therapy as an adjunct to transurethral resection of bladder tumor not only provides no benefit to patients with primary osteosarcoma of urinary bladder, but also may be associated with poor quality of life.
原发性骨肉瘤是一种罕见的累及膀胱的肿瘤。在一名有长期膀胱移行细胞癌病史的患者中发生骨肉瘤的情况更为罕见。
我们报告一例74岁的希腊男性病例，他在被诊断患有膀胱移行细胞癌10年后被诊断出骨肉瘤，在过去三年中他的膀胱移行细胞癌未复发。我们的患者接受了经尿道膀胱肿瘤切除术和体外放射治疗以治疗骨肉瘤。他在诊断后八个月去世，在最后几个月生活质量较差。
膀胱骨肉瘤预后不佳。体外放射治疗作为经尿道膀胱肿瘤切除术的辅助治疗，不仅对原发性膀胱骨肉瘤患者没有益处，而且可能与生活质量差有关。
