Zhang Zong-jiu, Zhang Peng, Tian Jin-hui, Li Jun, Li Lun, Tian Jing, Yang Ke-hu
Lanzhou University, Lanzhou, China, Ministry of Public Health, Beijing, China.
Surg Innov. 2010 Mar;17(1):41-7. doi: 10.1177/1553350610362084.
To evaluate the effect of ultrasonic coagulator for thyroidectomy.
randomized controlled trials were searched in PubMed, EMBASE, Cochrane Library, SCI, Chinese Biomedical Database, China Academic Journals Full-Text Database, Chinese Scientific Journals Database, and China Online Journals. The authors evaluated the quality of included studies by Handbook 5.0.0, and analyzed data by Cochrane Collaboration's RevMan 5.0.
A total of 11 RCTs with 1420 patients met the criteria. Between ultrasonic coagulator and conventional technique, there were significant differences in operative time of total thyroidectomy (P < .00001) and amount of intraoperative bleeding (P = .02). There were no significant differences in operative time of part thyroidectomy (P = .07), amount of postoperative drainage (P = .18), cases of transient hypocalcemia (P = .41), cases of transient recurrent nerve paresis (P = .21), and total cost in hospital (P = .08).
Current studies demonstrate that ultrasonic coagulator has a significant reduction on the operating time of total thyroidectomy and the amount of intraoperative bleeding in thyroidectomy, without increasing complications and total cost in hospital.
评估超声刀在甲状腺切除术中的应用效果。
检索PubMed、EMBASE、Cochrane图书馆、SCI、中国生物医学数据库、中国学术期刊全文数据库、中国科学期刊数据库和中国在线期刊中的随机对照试验。作者采用《手册5.0.0》评估纳入研究的质量，并使用Cochrane协作网的RevMan 5.0进行数据分析。
共有11项随机对照试验、1420例患者符合标准。在全甲状腺切除术的手术时间（P <.00001）和术中出血量方面（P =.02），超声刀组与传统技术组之间存在显著差异。在部分甲状腺切除术的手术时间（P =.07）、术后引流量（P =.18）、暂时性低钙血症病例数（P =.41）、暂时性喉返神经麻痹病例数（P =.21）和住院总费用方面（P =.08），两组之间无显著差异。
目前的研究表明，超声刀在甲状腺切除术中可显著缩短全甲状腺切除术的手术时间并减少术中出血量，且不增加并发症和住院总费用。
