Department of Urology, University Hospital Grosshadern, Ludwig-Maximilians-University Munich, 81377 Munich, Germany.
World J Urol. 2010 Apr;28(2):169-72. doi: 10.1007/s00345-010-0520-z. Epub 2010 Feb 25.
To review the indication, feasibility and treatment outcome of Ho:YAG laser application for definitive endoscopic treatment of anastomotic stricture formation after radical prostatectomy.
Currently, no universally accepted regime for managing post-prostatectomy anastomotic strictures exists. Cold knife incision is the most commonly utilized invasive technique for the treatment of bladder neck contractures. The Ho:YAG laser with its shallow tissue absorption of <0.5 mm offers favorable cutting properties including low blood loss and less induction of scar tissue formation and could be a valid alternative to endoscopic knife incision.
PubMed and Medline were searched for reports on Ho:YAG laser therapy in strictures from 1980 to 2009 with particular focus on the operating techniques using the Ho:YAG laser system.
Ho:YAG laser endourethrotomy tends to be a safe and at least minimally invasive therapeutic modality for the treatment of bladder neck contractures after radical prostatectomy. No cohort study that evaluates the use of laser for this modality is available in literature. Due to the lack of comparable randomized multicentre trials, the indications for a laser-related endoscopic treatment option has to be defined based on the operators expertise and the patient's individual situation.
回顾钬：YAG 激光在根治性前列腺切除术后吻合口狭窄的确定性内镜治疗中的适应证、可行性和治疗效果。
目前，尚无公认的管理前列腺切除术后吻合口狭窄的方案。冷刀切开术是治疗膀胱颈部挛缩最常用的侵袭性技术。钬：YAG 激光的组织浅层吸收率<0.5mm，具有良好的切割特性，包括出血量少，较少诱导瘢痕组织形成，可能是内镜刀切开术的有效替代方法。
在 1980 年至 2009 年期间，通过 PubMed 和 Medline 搜索了关于钬：YAG 激光治疗狭窄的报告，特别关注使用钬：YAG 激光系统的手术技术。
钬：YAG 激光尿道内切开术是治疗根治性前列腺切除术后膀胱颈部挛缩的一种安全、至少微创的治疗方法。目前，文献中尚无评估激光在该方法中的应用的队列研究。由于缺乏可比的随机多中心试验，因此必须根据操作人员的专业知识和患者的个体情况来确定激光相关内镜治疗选择的适应证。
