Feng Xin, Wang Jun-Song, Luo Jun, Kong Ling-Yi
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
J Asian Nat Prod Res. 2009 Jul;11(7):675-80. doi: 10.1080/10286020903002121.
Two new sesquiterpene glycosides, 11R,12-dihydroxy-6(7)-spirovetiven-8-one-9-O-beta-D-glucopyranoside (1) and rishitin M1-13-O-beta-D-glucopyranoside (2), have been isolated from the leaves of Nicotiana tabacum. Their structures were established by spectroscopic methods including (1)H, (13)C, and 2D NMR. The absolute configuration of the side chain in compound 1 was determined as R by NOESY and NOE difference spectra.
从烟草叶片中分离出了两种新的倍半萜糖苷，11R,12-二羟基-6(7)-螺岩兰草烯-8-酮-9-O-β-D-吡喃葡萄糖苷(1)和瑞西丁素M1-13-O-β-D-吡喃葡萄糖苷(2)。通过包括(1)H、(13)C和二维核磁共振在内的光谱方法确定了它们的结构。通过NOESY和NOE差谱确定化合物1中侧链的绝对构型为R。
