一种来自角果木的新型多拉烷型二萜。

A new dolabrane-type diterpene from Ceriops tagal.

作者信息

Ouyang Xiao-Wei, Wang Xia-Chang, Yue Qing-Xi, Hu Li-Hong

机构信息

Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai, 201203, P. R. China.

出版信息

Nat Prod Commun. 2010 Jan;5(1):9-12.

PMID:20184010

Abstract

A new dolabrane-type diterpene named tagalsin O 1, together with six known analogues 2-7, were isolated from the aerial part of the mangrove plant Ceriops tagal. The structures and relative configurations were elucidated on the basis of their spectroscopic data. Cytotoxicity of the isolated compounds against HeLa human cervical carcinoma cancer cell line was evaluated.

摘要

从红树植物角果木的地上部分分离出一种名为tagalsin O 1的新型多拉烷型二萜，以及六种已知类似物2 - 7。根据光谱数据阐明了它们的结构和相对构型。评估了分离出的化合物对HeLa人宫颈癌细胞系的细胞毒性。