Hartman V, Van Hee R
Academic Surgical Center Stuivenberg, University of Antwerp, Antwerp, Belgium.
Acta Chir Belg. 2009 Nov-Dec;109(6):760-2. doi: 10.1080/00015458.2009.11680531.
Two patients with acute colonic pseudo-obstruction are presented. Acute colonic pseudo-obstruction, first described by Ogilvie in 1948, is characterised by signs of colonic obstruction, but without mechanical obstruction to the intestinal flow. The current hypothesis states that it is caused by an imbalance between sacral parasympathetic excitatory nerves and sympathetic inhibitory nerves, thus inducing functional obstruction. It mostly develops in hospitalised patients with a variety of medical and surgical conditions. Two such patients with extensive co-morbidities, developed progressive colon dilatation with signs of acute peritonitis, and were operated on urgently. In both patients, right hemicolectomy and postoperative medical treatment resulted in complete recovery.
本文介绍了两名急性结肠假性梗阻患者。急性结肠假性梗阻由奥吉尔维于1948年首次描述，其特征为结肠梗阻的体征，但肠道并无机械性梗阻。目前的假说是，它是由骶副交感神经兴奋性神经和交感神经抑制性神经之间的失衡引起的，从而导致功能性梗阻。它大多发生在患有各种内科和外科疾病的住院患者中。两名患有多种合并症的此类患者出现了进行性结肠扩张并伴有急性腹膜炎体征，遂紧急接受手术。两名患者均接受了右半结肠切除术及术后药物治疗，最终完全康复。
