Chang Y-M, Hsu K-F, Chang S-C
Department of Plastic Surgery, Tri-Service General Hospital, National Defence Medical Centre, Taipei, Taiwan, Republic of China.
Acta Chir Belg. 2009 Nov-Dec;109(6):808-10. doi: 10.1080/00015458.2009.11680545.
Extra-mammary Paget's disease is a rare disease mainly observed in elderly patients. It is an intra-epithelial adenocarcinoma that involves the area rich in apocrine glands. The most common affected lesions are the vulva and perianal region, followed by the axillae and inguinoscrotal area. Mostly, extra-mammary Paget's disease is restricted to the epidermis, but advanced invasion to the dermis is possible with a poor prognosis of disease. The associated occult malignancy is reported and often exists for more than 10 years without clinical manifestation. We report a case of a 66-year-old male with extra-mammary Paget's disease of the scrotum and penis. The diagnosis and treatment are discussed.
乳房外佩吉特病是一种罕见疾病，主要见于老年患者。它是一种上皮内腺癌，累及富含顶泌汗腺的区域。最常受累的部位是外阴和肛周区域，其次是腋窝和腹股沟阴囊区。大多数情况下，乳房外佩吉特病局限于表皮，但也可能进展至真皮，疾病预后较差。有报道称存在相关隐匿性恶性肿瘤，且常隐匿存在超过10年而无临床表现。我们报告一例66岁男性阴囊和阴茎的乳房外佩吉特病病例，并对其诊断和治疗进行讨论。
