Ecole Normale Supérieure, Département de Chimie, UMR CNRS-ENS-UPMC 8640 Pasteur, 24 rue Lhomond, F-75231 Paris Cedex 05, France.
Anal Chem. 2010 Mar 15;82(6):2434-40. doi: 10.1021/ac902788v.
Microband arrays improve the analytical performance and information content of electrochemical detection in flow channel relative to single-electrode configurations. However, exploiting their full advantages requires a detailed understanding of the properties of arrays, which depend on their geometry and on the hydrodynamic regimes established inside the microfluidic channel. This paper investigates the influence of two main operating situations (sequential and coupling regimes) on steady-state amperometric responses of microband arrays performing under laminar flow conditions. Simulations and experimental measurements showed that the resulting properties of the arrays are a function of the number of electrodes and average ratio between gaps and electrode widths, whether the layout of the arrays is regular or not. Since the contribution of each electrode can be finely tailored, this allows the arrays to be designed and adapted to a wide variety of experimental demands.
微带阵列相对于单电极结构提高了电化学检测在流动通道中的分析性能和信息含量。然而，要充分发挥其优势，需要详细了解其性能，而这些性能取决于其几何形状和微流道内建立的流体动力学状态。本文研究了两种主要工作情况（顺序和耦合状态）对在层流条件下工作的微带阵列稳态安培响应的影响。模拟和实验测量表明，阵列的特性是电极数量和电极宽度与间隙之比的平均值的函数，无论阵列的布局是否规则。由于每个电极的贡献都可以精细地调整，因此可以对其进行设计，并适应各种不同的实验需求。
