Burhol P G
Department IX, Ullevål Hospital, Oslo, Norway.
Scand J Gastroenterol. 1967;2(2):157-9. doi: 10.3109/00365526709180061.
Total nitrogen, volume rate, total HCl and chloride were determined in the gastric juice of 12 patients with gastric cancer and of 17 patients with a clinical diagnosis of peptic gastric ulcer, before and after subcutaneous injection of large doses of histamine. The mean concentration of total nitrogen in the gastric juice of the patients with gastric cancer was significantly higher than in those with gastric ulcer, whereas no significant differences were found between the corresponding mean values of volume rates and concentrations and outputs of total HCl and chloride in the gastric juice of these groups of patients. It is suggested that estimation of total nitrogen concentration in the gastric juice may differentiate between cancer and peptic gastric ulcer of the stomach with a higher degree of certainty than estimation of volume rate, total HCl, or chloride.
在12例胃癌患者和17例临床诊断为消化性胃溃疡的患者皮下注射大剂量组胺前后，测定其胃液中的总氮、容量率、总盐酸和氯化物。胃癌患者胃液中总氮的平均浓度显著高于胃溃疡患者，而这两组患者胃液的容量率、总盐酸和氯化物的相应平均浓度及排出量之间未发现显著差异。提示，与容量率、总盐酸或氯化物的测定相比，胃液中总氮浓度的测定可能更能准确地区分胃癌和胃消化性溃疡。
