Blogg J R
Armadale Veterinary Eye Hospital, Victoria.
Aust Vet J. 1991 Jan;68(1):8-9. doi: 10.1111/j.1751-0813.1991.tb09829.x.
Chloramphenicol has gained widespread use in the topical treatment of ocular infections. The rationale for this use was based on the ability of chloramphenicol to penetrate the cornea and enter the anterior segment, together with its broad spectrum of antimicrobial activity. However, routine use in corneal ulceration or keratitis is not desirable. Hypopyon, when present, is usually sterile. Concerns about human exposure to chloramphenicol and its recent prohibition of use in food-producing animals, raise the need to review its indications and discuss alternatives. The role of chloramphenicol in ocular therapeutics is examined in this article.
氯霉素已广泛用于眼部感染的局部治疗。这种应用的理论依据是氯霉素能够穿透角膜并进入眼前段，以及其广泛的抗菌活性。然而，在角膜溃疡或角膜炎中常规使用并不理想。当出现前房积脓时，通常是无菌的。由于担心人类接触氯霉素以及最近禁止在食用动物中使用，因此有必要审查其适应证并讨论替代药物。本文探讨了氯霉素在眼部治疗中的作用。
