Rizzo Stefania, Monfardini Lorenzo, Belmonte Maddalena, Rocco Bernardo, Belloni Massimo
Department of Radiology, European Institute of Oncology, via Ripamonti 435, Milan, 20141, Italy.
Cases J. 2009 Sep 11;2:8982. doi: 10.1186/1757-1626-0002-0000008982.
Splenosis is a post-traumatic autotrasplantation and proliferation of splenic tissue in ectopic sites. These implants may mimic malignancy in healthy patients or peritoneal metastases in cancer patients. When a previous history of splenic injury is known, the finding of soft tissue nodules in many thoracic and abdominal locations might raise the suspicion of the benign condition of splenosis, in order to avoid unnecessary surgery or chemotherapy.
A 56-year-old man with history of persistent hematuria from bladder cancer was referred to our Institution for suspected peritoneal carcinosis. For staging purposes he underwent abdominal computed tomography and ultrasound. The integration of patient's history and imaging results led to the diagnosis of peritoneal splenosis. The patient therefore underwent regular Trans Urethral Resection of Bladder for the known malignancy; while no treatment was necessary for splenosis. Two years follow-up was negative for metastases.
Splenosis is a benign condition after traumatic splenectomy which should be taken into account in the differential diagnosis with peritoneal seeding of malignancy because its appearance may resemble malignancy.
脾组织移植是脾组织在创伤后于异位部位进行自体移植和增殖。这些植入物在健康患者中可能类似恶性肿瘤，在癌症患者中可能类似腹膜转移瘤。当已知有脾损伤既往史时，在许多胸腹部位置发现软组织结节可能会引发对脾组织移植这一良性病症的怀疑，以避免不必要的手术或化疗。
一名56岁男性，有膀胱癌导致持续性血尿病史，因疑似腹膜癌转移被转诊至我院。为进行分期评估，他接受了腹部计算机断层扫描和超声检查。综合患者病史和影像学结果，诊断为腹膜脾组织移植。因此，该患者因已知的恶性肿瘤接受了常规经尿道膀胱肿瘤切除术；而脾组织移植无需治疗。两年随访未发现转移。
脾组织移植是外伤性脾切除术后的一种良性病症，在与恶性肿瘤腹膜播散的鉴别诊断中应予以考虑，因为其表现可能类似恶性肿瘤。
