Comstedt Lisbeth Rosholm, Gregersen Janni Hjortlund, Bygum Anette
Odense Universitetshospital, Hudafdeling I og Allergicentret, Denmark.
Ugeskr Laeger. 2010 Feb 22;172(8):628-9.
Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous drug reaction often caused by beta-lactam antibiotics. The reaction is characterized by sudden occurrence of a generalized exanthema, developing within 1-2 days. Hundreds of sterile pustules arise on an oedematous and erythematous base. The cutaneous symptoms are accompanied by fever and neutrophilia. The pustules resolve within 4-10 days once the causative drug has been withdrawn. We hereby present a classical case of amoxicillin-induced AGEP in a 34-year-old woman.
急性泛发性脓疱性皮病（AGEP）是一种罕见的皮肤药物反应，通常由β-内酰胺类抗生素引起。该反应的特征是在1-2天内突然出现全身性皮疹。在水肿性和红斑性基底上出现数百个无菌脓疱。皮肤症状伴有发热和中性粒细胞增多。一旦停用致病药物，脓疱在4-10天内消退。我们在此呈现一例34岁女性由阿莫西林引起的AGEP经典病例。
