阿莫西林和克拉维酸所致局限性急性泛发性脓疱病

Localized acute generalized exanthematous pustulosis with amoxicillin and clavulanic acid.

作者信息

Ozkaya-Parlakay Ashinur, Azkur Dilek, Kara Ateş, Yildiz Yilmaz, Orhan Diclehan, Cengiz A Bülent, Ersoy-Evans Sibel

机构信息

Department of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Turk J Pediatr. 2011 Mar-Apr;53(2):229-32.

PMID:21853667

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare skin disorder, characterized by acute development of numerous, pin-head sized, nonfollicular pustules on erythematous skin, with high fever and neutrophilia. The condition is frequently caused by hypersensitivity reaction to drugs or viral infections. Diagnosis is established according to clinical and histological criteria. Herein, we report a 17-year-old girl with localized AGEP related to the use of amoxicillin-clavulanate.

摘要

急性泛发性脓疱性皮病（AGEP）是一种罕见的皮肤疾病，其特征为在红斑皮肤上急性出现大量针头大小的非毛囊性脓疱，并伴有高热和中性粒细胞增多。这种情况常由药物过敏反应或病毒感染引起。诊断依据临床和组织学标准确立。在此，我们报告一名17岁女孩，其局限性AGEP与使用阿莫西林-克拉维酸有关。